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CVE-2026-31967

9.1 · CRITICAL
Published Mar 18, 2026 htslib CWE-125

Overview

CVE-2026-31967 is a critical-severity vulnerability affecting htslib htslib. It was published on March 18, 2026 and has a CVSS 3.1 base score of 9.1 (CRITICAL).

This vulnerability has a CVSS 3.1 base score of 9.1, rated CRITICAL. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

Technical Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. In the `cram_decode_slice()` function called while reading CRAM records, the value of the mate reference id field was not validated. Later use of this value, for example when converting the data to SAM format, could result in the out of bounds array reads when looking up the corresponding reference name. If the array value obtained also happened to be a valid pointer, it would be interpreted as a string and an attempt would be made to write the data as part of the SAM record. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Remediation

Check the references section for vendor advisories and patches from htslib. Update htslib to the latest patched version. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

Affected Products

Vendor Product Versions Status
htslib htslib >= 0, < 1.21.1 Affected

Frequently Asked Questions

What is CVE-2026-31967?

CVE-2026-31967 is a critical-severity vulnerability affecting htslib htslib. It was published on March 18, 2026 and has a CVSS 3.1 base score of 9.1 (CRITICAL).

How severe is CVE-2026-31967?

This vulnerability has a CVSS 3.1 base score of 9.1, rated CRITICAL. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

How do I fix or remediate CVE-2026-31967?

Check the references section for vendor advisories and patches from htslib. Update htslib to the latest patched version. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

How can CyberStrike help with CVE-2026-31967?

CyberStrike's AI-powered security agents can automatically detect CVE-2026-31967 across your infrastructure using autonomous pentesting, DAST scanning, and HackBrowser. The platform continuously monitors for known vulnerabilities and provides actionable remediation guidance prioritized by real-world exploitability.

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