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CVE-2026-31969

8.1 · HIGH
Published Mar 18, 2026 htslib CWE-122

Overview

CVE-2026-31969 is a high-severity vulnerability affecting htslib htslib. It was published on March 18, 2026 and has a CVSS 3.1 base score of 8.1 (HIGH).

This vulnerability has a CVSS 3.1 base score of 8.1, rated HIGH. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

Technical Description

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data using a variety of encodings and compression methods. When reading data encoded using the `BYTE_ARRAY_STOP` method, an out-by-one error in the `cram_byte_array_stop_decode_char()` function check for a full output buffer could result in a single attacker-controlled byte being written beyond the end of a heap allocation. Exploiting this bug causes a heap buffer overflow. If a user opens a file crafted to exploit this issue, it could lead to the program crashing, or overwriting of data and heap structures in ways not expected by the program. It may be possible to use this to obtain arbitrary code execution. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

Remediation

Check the references section for vendor advisories and patches from htslib. Update htslib to the latest patched version. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

Affected Products

Vendor Product Versions Status
htslib htslib >= 0, < 1.21.1 Affected

Frequently Asked Questions

What is CVE-2026-31969?

CVE-2026-31969 is a high-severity vulnerability affecting htslib htslib. It was published on March 18, 2026 and has a CVSS 3.1 base score of 8.1 (HIGH).

How severe is CVE-2026-31969?

This vulnerability has a CVSS 3.1 base score of 8.1, rated HIGH. It can be exploited remotely over the network. No authentication or special privileges are required for exploitation.

How do I fix or remediate CVE-2026-31969?

Check the references section for vendor advisories and patches from htslib. Update htslib to the latest patched version. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.

How can CyberStrike help with CVE-2026-31969?

CyberStrike's AI-powered security agents can automatically detect CVE-2026-31969 across your infrastructure using autonomous pentesting, DAST scanning, and HackBrowser. The platform continuously monitors for known vulnerabilities and provides actionable remediation guidance prioritized by real-world exploitability.

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