CVE-2026-54604
OpenSlide is a C library for reading whole slide image files.
Overview
CVE-2026-54604 is a known-severity vulnerability. It was published on September 17, 2026.
Technical description
OpenSlide is a C library for reading whole slide image files. Prior to 4.0.1, a behavior change in libtiff 4.7.1 causes the indirect TIFF tile path in src/openslide-decode-tiff.c and _openslide_tiff_read_tile() to request a full-height destination for a partial bottom tile row, allowing uninitialized heap memory to enter pixel data returned by openslide_read_region(). A crafted but valid slide can trigger the issue in TIFF-based formats other than Hamamatsu NDPI when a network service renders attacker-provided slides. Successful extraction depends on pixel transparency handling and recompression, OpenSlide with libtiff 4.7.0 or earlier is not affected, and official binary builds 4.0.0.10 and 4.0.0.11 are affected. This issue is fixed in OpenSlide 4.0.1 and official binary build 4.0.0.12.
Remediation
Check the references section for vendor advisories, patches, and mitigation guidance. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.
References
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Frequently asked questions
What is CVE-2026-54604?
CVE-2026-54604 is a known-severity vulnerability. It was published on September 17, 2026.
How severe is CVE-2026-54604?
CVSS score information is not yet available for this vulnerability. Check back as the CVE record is updated by NVD analysts.
How do I fix or remediate CVE-2026-54604?
Check the references section for vendor advisories, patches, and mitigation guidance. If immediate patching is not possible, review the CVSS vector to understand the attack surface and apply compensating controls such as network segmentation or access restrictions.
How can CyberStrike help with CVE-2026-54604?
CyberStrike is an open-source, AI-augmented pentesting engine. Rather than flag a version number, it tests whether an issue like CVE-2026-54604 is actually reachable in your own applications and APIs, then verifies each finding before reporting it. That tells you if the weakness is a real, exploitable risk in your environment or a false positive you can safely deprioritize.